Our Client is a Biotechnology company that is developing high throughput quantitative biochemical assays for the pharmaceutical industry.
The challenge for the holder of the Experimental Physicist/Engineer position will be the planning and assembly of a computer-controlled micro-fluidics device integrated with optical instrumentation to perform time-resolved fluorescence resonant energy transfer (TR-FRET) in total internal reflection (TIR) geometry on a multiplexed chip array. Key tasks for this post will be the the micro-fluidics set-up assembly and the hardware software-interfacing of the micro-fluidics device integrated with the acquisition of TR-FRET measurements.
The post will require a dynamic flexible approach and the ability to interact with Biologists / Biochemists, and Chemists. The Experimental Physicist/Engineer will be responsible for the delivery a series of technical goals with tight deadlines.
Main Function of Post: To carry out experimental work for the development of a computer-controlled automated instrument performing high-throughput time-resolved fluorescence resonant energy transfer (TR-FRET) measurements in total internal reflection (TIR) geometry on a multiplexed chip array integrated into a micro-fluidics device.
- Planning and assembly of a computer-controlled micro-fluidics device.
- To contribute to the planning and assembly of an optical set-up for TR-FRET in TIR geometry.
- Hardware-software interfacing for automated computer-controlled measurements and data acquisition.
- Excellent knowledge of micro-fluidics
- Excellent knowledge of electronics
- Excellent knowledge of computer programming
- Good knowledge of optics
- Excellent expertise and competence of operating principles and performances of micro-fluidics-related instrumentation
- Excellent practical skills with micro-fluidics instrumentation
- Excellent practical skills with electronics
- Excellent practical skills with programming for hardware interfacing
- Excellent practical skills with software for quantitative data analysis.
- Good practical skills with optical microscopy instrumentation
- Excellent organisational skills with a proven ability to prioritise and meet deadlines within the framework of an agreed programme.
- Excellent written and verbal communication skills
- A PhD in Engineering or Physics or other relevant equivalent research experience.
- A demonstrable history of practical laboratory work developing micro-fluidics-related instrumentation
- A demonstrable history of hardware-software interfacing
Specific Qualities (eg attitudes)
- Ambitious and committed to scientific excellence
- Committed to precision, accuracy and task completion.
- Self-motivated and able to work with limited supervision.
- Flexible, responsible approach to working in a multi-tasking and multi-disciplinary environment.
- Experience with micro-fluidic devices for optical microscopy
- Knowledge of biochemistry techniques
Please contact: Ian Ashforth <firstname.lastname@example.org>