Research Scientist — Daktari Diagnostics

Position: Research Scientist

Daktari Diagnostics, Inc. is a Boston-based company developing innovative diagnostic tests for global health conditions. The core technology combines microfluidics with electrochemical sensing. Our initial product, a point-of-care CD4 testing system for use in HIV disease staging worldwide, will provide a CD4 cell count result in less than 10 minutes from a finger stick of blood, anywhere in the world. This handheld system includes a low-cost electromechanical instrument and a disposable assay cartridge comprised of molded plastics, microfluidics, integrated sensors, and chemistry.

The successful candidate will work as part of an actively growing research team and will focus on moving the CD4 counting product further into the late stages of product development and/or on the discovery phase of new diagnostics products. Emphasis will be placed on the ability to design experiments and analyze results. Must be able to work independently as well as make significant contributions to multi-site collaborative efforts.

Responsibilities include, but are not limited to:

  • Design and conduct experiments to optimize immunoassay performance and analyze results
  • Design and conduct experiments to optimize microfluidic assay performance and study the interactions between biological samples (e.g., blood, cells, virions) and the microfluidics cartridge
  • Design and conduct proof-of-concept experiments for new diagnostic products
  • Develop and validate on-board dry reagent (antibody, magnetic particles) and wet reagent (buffer) chemistry for a stable and robust microfluidics-based point-of-care assay
  • Design and manage studies to assess reagent and assay kit stability
  • Prepare technical reports
  • Write Standard Operating Procedures, and transfer technology to production group
  • Perform all duties in compliance with appropriate quality system regulations and GLP standards
  • Support data collection and documentation for submission to regulatory agencies

Requirements:

  • PhD degree in biology, chemistry, biomedical/biological engineering or related field
  • 1−5 years of experience in immunoassay development, preferably in a commercial setting
  • Experience in development of microfluidics-based systems strongly preferred
  • Experience with handling biological samples including human bodily fluids and bacterial and viral cultures preferred
  • Experience in medical diagnostic device development a plus
  • Ability to work independently in a start-up environment
  • Excellent communication skills and ability to present scientific data to senior staff

Daktari Diagnostics is a dynamic, start-up environment committed to bringing the highest quality medical diagnostics to everyone, everywhere.
Please submit resume to work@daktaridx.com and reference code RD15.

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