Tag Archives: lab-on-a-chip

NIH / DARPA solicit proposals for human-on-chip platforms to accelerate drug development

Fantastic to hear about a new, substantial U.S. government funding effort in microfluidics research! Last month a joint effort between the NIH, DARPA, and the FDA was announced to develop human-on-chip platforms to test drug candidates more efficiently and accurately. The NIH and DARPA are soliciting proposals separately from all types of research organizations (academic, industry, government, other) […]

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MICROmanufacturing Magazine interviews Don Ingber of the Wyss Institute

Just came across this MICROmanufacturing Magazine interview with Wyss Institute Founding Director, Don Ingber, about their microfluidic organ-on-a-chip work led by Ingber and Dan Dongeun Huh. Interesting to see the interview delve into a manufacturing question, highlighting the translational nature of the Wyss: MICRO: How are these devices being manufactured? Ingber: Manufacturing has been done […]

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Microfluidics and food safety

Could microfluidic technology help deliver safer food?  While most lab-on-a-chip devices are aimed at the medical and life science research markets, a growing number of researchers and companies are investigating applications related to food and agriculture. The recent E. coli outbreak in Germany showed how devastating foodborne illness can be, in terms of human life, […]

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BVGH’s Diagnostics Innovation Map for Global Health

In the past few years, more diagnostics companies have been directing efforts toward global health. Many are hoping to tap into the “boomerang effect” — the concept that cheap technologies optimized for the developing world could boomerang back to access additional markets in the G7. This year BIO Ventures for Global Health (BVGH) issued a […]

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Michael Vahey wins Senturia Prize for microfluidic / isodielectric cell screening method

I’m happy to announce that Michael Vahey, a former colleague from the Voldman lab at MIT, has won this year’s Senturia Prize for his Ph.D. thesis work on a novel microfluidic technique for separating and characterizing cells according to their electrical properties. This method offers a new tool for biologists looking to screen millions of […]

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DIY microfluidics

Image credit: Kumar, Smith, Pappas 2009 Lately there’s been talk about the DIY Bio movement enabling individuals to do real biology without being part of a university/company lab.  Given its potential for low-cost and quick prototyping, microfluidics seems to have promising overlap with DIY Bio.  But how would one actually get started with a DIY […]

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Watch this space: Jose Gomez-Marquez’s lab at MIT’s IIH

If you’re interested in international development and microfluidics, check out Jose Gomez-Marquez’s group at MIT — they’re at the forefront of creating technologies for global health as part of the Innovations in International Health (IIH) program.  Gomez-Marquez has a wealth of experience in medical technologies for the developing world, having co-founded AeroVax and XoutTB.  In […]

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Claros Diagnostics in Tech Review

Claros Diagnostics, who spoke at the first FluidicMEMS event, is on a roll. In the past few weeks their microfluidic technology for monitoring levels of prostate specific antigen (PSA) has been covered in both Technology Review and Popular Science (April 2010 issue). From the Technology Review article (March 31, 2010): Claros’s technology, which consists of […]

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Recent clinical trials of microfluidic devices

After I heard about a clinical trial for a microfluidic device that detects circulating cancer cells, I started wondering how many other microfluidic devices are in clinical trials.  A quick search turned up only seven studies (and two of those were withdrawn). Interestingly, five of the seven trials have some connection to the University of […]

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Microfluidics for studying cancer metastasis

What causes cancer cells to become metastatic, moving beyond their local environment to infiltrate other parts of the body? Some researchers have called metastasis “the most dangerous event in cancer,” and many believe that a better understanding of metastasis could lead to new cancer treatments. Microfluidics researchers have long been investigating metastasis, because metastasis is […]

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